Games / MLB / May 21, 2025

Cleveland Guardians 5, Minnesota Twins 1: final score and stats

Cleveland Guardians beat Minnesota Twins, Cleveland Guardians 5 to Minnesota Twins 1, on Wednesday, May 21, 2025 at Target Field, Minneapolis, Minnesota. Below: the box score, top performers, team stats, injuries and recent form for Minnesota Twins vs Cleveland Guardians.

MLBWednesday, May 21, 2025

Cleveland Guardians26-225

Final

Minnesota Twins27-221

DateMay 21, 2025

Start time3:55 PM ET

VenueTarget Field, Minneapolis, Minnesota

TVMLB.TV, CLEGuardians.TV, MLBN, Twins.TV

Attendance26,142

Line score

Team	1	2	3	4	5	6	7	8	9	R
Cleveland Guardians	0	0	0	0	0	2	0	1	2	5
Minnesota Twins	0	0	1	0	0	0	0	0	0	1

Top performers

Cleveland Guardians

Batting AverageCarlos Santana · 2-3, HR, RBI, 2 R, BB

Home RunsCarlos Santana · 2-3, HR, RBI, 2 R, BB

Runs Batted InCarlos Santana · 2-3, HR, RBI, 2 R, BB

MLB RatingCarlos Santana · 2-3, HR, RBI, 2 R, BB

Minnesota Twins

Batting AverageHarrison Bader · 1-3, BB

Home RunsChristian Vazquez · 0-3

Runs Batted InRyan Jeffers · 1-3, RBI

MLB RatingRyan Jeffers · 1-3, RBI

Team comparison

Cleveland GuardiansMinnesota Twins

Runs per game

-

-

Runs allowed per game

-

-

26-22Record27-22

1st in AL CentStanding3rd in AL Cent

0-0Road record / home record0-0

Last 5

-Streak-

Injury report

Confirm lineups and injuries close to game time.

Cleveland Guardians

Colin Holderman RP · Wrist - Surgery

Out

Kahlil Watson RF · Abdomen - Surgery

Out

Andrew Walters RP · Elbow - Surgery

Out

Minnesota Twins

Trevor Larnach LF · Wrist - Surgery

Out

Cole Sands RP · Elbow - Surgery

Out

David Festa SP · Shoulder - Surgery

Out

Mick Abel SP · Elbow - Surgery

Out

Anthony Banda RP · Lat - Surgery

Out

Box score

Cleveland Guardians

Player	H-AB	AB	R	H	RBI	HR	BB	K	#P	AVG	OBP	SLG
Steven Kwan	3-5	5	1	3	0	0	0	1	20	.317	.377	.439
Angel Martinez	0-4	4	0	0	1	0	0	1	16	.282	.308	.373
Jose Ramirez	3-5	5	1	3	1	0	0	1	20	.304	.363	.520
Kyle Manzardo	0-5	5	0	0	0	0	0	1	22	.216	.304	.480
Carlos Santana	2-3	3	2	2	1	1	1	0	15	.231	.337	.363
Daniel Schneemann	1-3	3	0	1	0	0	1	0	18	.265	.342	.490
Gabriel Arias	0-3	3	0	0	1	0	1	2	23	.243	.304	.375
Nolan Jones	1-2	2	0	1	1	0	0	0	14	.189	.283	.297
Jhonkensy Noel	1-1	1	1	1	0	0	0	0	1	.160	.188	.259
Austin Hedges	0-4	4	0	0	0	0	0	0	7	.130	.245	.326
Team	11-35	35	5	11	5	1	3	6	156

Cleveland Guardians

Player	IP	H	R	ER	BB	K	HR	PC-ST	ERA	PC
Gavin Williams	6.0	2	1	1	2	6	0	98-60	3.94	98
Tim Herrin	1.0	0	0	0	1	0	0	20-13	4.24	20
Hunter Gaddis	1.0	0	0	0	0	1	0	12-9	0.95	12
Emmanuel Clase	1.0	1	0	0	0	0	0	15-9	4.50	15
Team	9.0	3	1	1	3	7	0	145-91		145

Minnesota Twins

Player	H-AB	AB	R	H	RBI	HR	BB	K	#P	AVG	OBP	SLG
Ryan Jeffers	1-3	3	0	1	1	0	0	0	19	.273	.364	.409
Brooks Lee	0-3	3	0	0	0	0	1	0	13	.235	.287	.370
Royce Lewis	0-4	4	0	0	0	0	0	0	11	.191	.255	.298
Kody Clemens	1-4	4	0	1	0	0	0	3	20	.318	.388	.682
Jonah Bride	0-4	4	0	0	0	0	0	1	21	.302	.340	.349
Harrison Bader	1-3	3	0	1	0	0	1	0	20	.282	.366	.427
Willi Castro	0-2	2	1	0	0	0	1	1	16	.233	.313	.369
DaShawn Keirsey Jr.	0-2	2	0	0	0	0	0	1	8	.113	.130	.170
Trevor Larnach	0-1	1	0	0	0	0	0	1	3	.249	.327	.412
Christian Vazquez	0-3	3	0	0	0	0	0	0	14	.205	.272	.315
Team	3-29	29	1	3	1	0	3	7	145

Minnesota Twins

Player	IP	H	R	ER	BB	K	HR	PC-ST	ERA	PC
Chris Paddack	5.1	7	2	2	2	2	0	91-61	3.98	91
Louis Varland	0.2	0	0	0	1	0	0	14-7	2.86	14
Griffin Jax	1.0	0	0	0	0	3	0	20-14	4.98	20
Cole Sands	1.0	1	1	1	0	1	1	20-14	2.61	20
Kody Funderburk	1.0	3	2	2	0	0	0	11-8	4.91	11
Team	9.0	11	5	5	3	6	1	156-104		156

Season series

CLE wins series 4-2

Sep 21, 2025CLE 2, MIN 6

Sep 20, 2025CLE 8, MIN 0

Sep 20, 2025CLE 6, MIN 0

Sep 19, 2025CLE 6, MIN 2

Team pages

Cleveland Guardians
Schedule, roster and stats

Minnesota Twins
Schedule, roster and stats

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Chicago White Sox5

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Washington Nationals66-96

Boston Red Sox1

New York Yankees4

San Diego Padres0

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Philadelphia Phillies9

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Frequently asked questions

Who won Cleveland Guardians vs Minnesota Twins?

Cleveland Guardians won, 5-1, on Wednesday, May 21, 2025.

What was the final score of Cleveland Guardians vs Minnesota Twins?

Cleveland Guardians 5, Minnesota Twins 1.

Who were the top performers?

Cleveland Guardians: Carlos Santana (2-3, HR, RBI, 2 R, BB batting average). Minnesota Twins: Harrison Bader (1-3, BB batting average).

Where is Cleveland Guardians vs Minnesota Twins played?

Target Field, Minneapolis, Minnesota.

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Independent analysis for information and entertainment. Not betting advice. Scores, schedules, records and injuries can change.