Games / MLB / Sep 21, 2025

Cleveland Guardians 2, Minnesota Twins 6: final score and stats

Minnesota Twins beat Cleveland Guardians, Cleveland Guardians 2 to Minnesota Twins 6, on Sunday, September 21, 2025 at Target Field, Minneapolis, Minnesota. Below: the box score, top performers, team stats, injuries and recent form for Minnesota Twins vs Cleveland Guardians.

MLBSunday, September 21, 2025

Cleveland Guardians84-722

Final

Minnesota Twins67-896

DateSep 21, 2025

Start time2:10 PM ET

VenueTarget Field, Minneapolis, Minnesota

TVCLEGuardians.TV, MLB.TV, Twins.TV

Attendance22,526

Line score

Team	1	2	3	4	5	6	7	8	9	R
Cleveland Guardians	2	0	0	0	0	0	0	0	0	2
Minnesota Twins	0	0	1	0	0	2	3	0	-	6

Top performers

Cleveland Guardians

Batting AverageJose Ramirez · 1-4, K

Home RunsSteven Kwan · 1-4, HR, RBI, R

Runs Batted InBo Naylor · 0-3, RBI

MLB RatingSteven Kwan · 1-4, HR, RBI, R

Minnesota Twins

Batting AverageJhonny Pereda · 2-4, 2B

Home RunsRoyce Lewis · 1-1, HR, 3 RBI, R

Runs Batted InRoyce Lewis · 1-1, HR, 3 RBI, R

MLB RatingRoyce Lewis · 1-1, HR, 3 RBI, R

Team comparison

Cleveland GuardiansMinnesota Twins

Runs per game

-

-

Runs allowed per game

-

-

84-72Record67-89

1st in AL CentStanding3rd in AL Cent

0-0Road record / home record0-0

Last 5

-Streak-

Injury report

Confirm lineups and injuries close to game time.

Cleveland Guardians

Colin Holderman RP · Wrist - Surgery

Out

Kahlil Watson RF · Abdomen - Surgery

Out

Andrew Walters RP · Elbow - Surgery

Out

Minnesota Twins

Trevor Larnach LF · Wrist - Surgery

Out

Cole Sands RP · Elbow - Surgery

Out

David Festa SP · Shoulder - Surgery

Out

Mick Abel SP · Elbow - Surgery

Out

Anthony Banda RP · Lat - Surgery

Out

Box score

Cleveland Guardians

Player	H-AB	AB	R	H	RBI	HR	BB	K	#P	AVG	OBP	SLG
Steven Kwan	1-4	4	1	1	1	1	0	0	15	.276	.335	.380
George Valera	0-2	2	1	0	0	0	2	0	22	.250	.382	.429
Jose Ramirez	1-4	4	0	1	0	0	0	1	16	.282	.359	.504
Kyle Manzardo	1-4	4	0	1	0	0	0	2	14	.236	.317	.456
Bo Naylor	0-3	3	0	0	1	0	0	0	19	.194	.283	.379
Gabriel Arias	0-3	3	0	0	0	0	0	2	18	.223	.275	.367
Petey Halpin	0-1	1	0	0	0	0	0	1	4	.250	.400	.250
Angel Martinez	0-3	3	0	0	0	0	0	0	9	.226	.269	.365
Daniel Schneemann	0-1	1	0	0	0	0	0	0	4	.210	.287	.363
CJ Kayfus	0-3	3	0	0	0	0	0	0	5	.212	.286	.407
Brayan Rocchio	1-3	3	0	1	0	0	0	0	11	.233	.292	.334
Team	4-31	31	2	4	2	1	2	6	137

Cleveland Guardians

Player	IP	H	R	ER	BB	K	HR	PC-ST	ERA	PC
Joey Cantillo	4.1	4	1	1	2	5	0	75-48	3.21	75
Erik Sabrowski	1.1	1	1	1	0	1	0	18-12	2.03	18
Matt Festa	0.1	1	1	1	0	0	1	5-4	4.24	5
Tim Herrin	0.2	2	2	2	0	1	0	12-9	5.05	12
Hunter Gaddis	0.1	1	1	1	0	1	1	9-5	3.23	9
Zak Kent	1.0	1	0	0	0	2	0	19-14	4.97	19
Team	8.0	10	6	6	2	10	2	138-92		138

Minnesota Twins

Player	H-AB	AB	R	H	RBI	HR	BB	K	#P	AVG	OBP	SLG
Byron Buxton	1-3	3	1	1	0	0	1	2	21	.266	.331	.541
Kody Clemens	2-4	4	1	2	1	0	0	0	11	.219	.289	.451
Austin Martin	1-4	4	1	1	0	0	0	1	18	.293	.381	.386
Trevor Larnach	0-3	3	0	0	0	0	0	2	12	.249	.324	.402
Royce Lewis	1-1	1	1	1	3	1	0	0	4	.241	.289	.399
Luke Keaschall	1-4	4	1	1	0	0	0	2	20	.304	.380	.448
Edouard Julien	0-2	2	0	0	0	0	1	0	9	.199	.292	.298
James Outman	0-1	1	0	0	0	0	0	1	6	.165	.241	.354
Brooks Lee	2-4	4	1	2	2	1	0	2	11	.241	.290	.381
Jhonny Pereda	2-4	4	0	2	0	0	0	0	11	.345	.387	.483
Ryan Fitzgerald	0-4	4	0	0	0	0	0	0	15	.222	.317	.472
Team	10-34	34	6	10	6	2	2	10	138

Minnesota Twins

Player	IP	H	R	ER	BB	K	HR	PC-ST	ERA	PC
Simeon Woods Richardson	5.0	3	2	2	2	3	1	80-47	4.27	80
Kody Funderburk	1.0	0	0	0	0	1	0	14-11	3.79	14
Pierson Ohl	1.0	0	0	0	0	0	0	9-8	5.67	9
Cole Sands	1.0	1	0	0	0	1	0	20-13	4.70	20
Travis Adams	1.0	0	0	0	0	1	0	14-9	6.97	14
Team	9.0	4	2	2	2	6	1	137-88		137

Season series

CLE wins series 4-2

Sep 21, 2025CLE 2, MIN 6

Sep 20, 2025CLE 8, MIN 0

Sep 20, 2025CLE 6, MIN 0

Sep 19, 2025CLE 6, MIN 2

Team pages

Cleveland Guardians
Schedule, roster and stats

Minnesota Twins
Schedule, roster and stats

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Frequently asked questions

Who won Cleveland Guardians vs Minnesota Twins?

Minnesota Twins won, 6-2, on Sunday, September 21, 2025.

What was the final score of Cleveland Guardians vs Minnesota Twins?

Cleveland Guardians 2, Minnesota Twins 6.

Who were the top performers?

Cleveland Guardians: Jose Ramirez (1-4, K batting average). Minnesota Twins: Jhonny Pereda (2-4, 2B batting average).

Where is Cleveland Guardians vs Minnesota Twins played?

Target Field, Minneapolis, Minnesota.

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Grades, leans and the full breakdown for Cleveland Guardians vs Minnesota Twins are on the board.

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Independent analysis for information and entertainment. Not betting advice. Scores, schedules, records and injuries can change.