Games / MLB / May 22, 2026

Houston Astros 4, Chicago Cubs 2: final score and stats

Houston Astros beat Chicago Cubs, Houston Astros 4 to Chicago Cubs 2, on Friday, May 22, 2026 at Wrigley Field, Chicago, Illinois. Below: the box score, top performers, team stats, injuries and recent form for Chicago Cubs vs Houston Astros.

MLBFriday, May 22, 2026

Houston Astros21-314

Final

Chicago Cubs29-222

DateMay 22, 2026

Start time2:20 PM ET

VenueWrigley Field, Chicago, Illinois

TVApple TV

Attendance37,332

Line score

Team	1	2	3	4	5	6	7	8	9	R
Houston Astros	0	0	1	2	1	0	0	0	0	4
Chicago Cubs	0	0	0	0	0	2	0	0	0	2

Top performers

Houston Astros

Batting AverageChristian Vazquez · 2-4, HR, 2 RBI, R, K

Home RunsChristian Vazquez · 2-4, HR, 2 RBI, R, K

Runs Batted InChristian Vazquez · 2-4, HR, 2 RBI, R, K

MLB RatingChristian Vazquez · 2-4, HR, 2 RBI, R, K

Chicago Cubs

Batting AveragePete Crow-Armstrong · 1-2, HR, 2 RBI, R, 2 BB

Home RunsPete Crow-Armstrong · 1-2, HR, 2 RBI, R, 2 BB

Runs Batted InPete Crow-Armstrong · 1-2, HR, 2 RBI, R, 2 BB

MLB RatingPete Crow-Armstrong · 1-2, HR, 2 RBI, R, 2 BB

Team comparison

Houston AstrosChicago Cubs

Runs per game

3.0

0.5

Runs allowed per game

6.5

6.0

21-31Record29-22

1st in AL WestStanding2nd in NL Cent

0-0Road record / home record0-0

LLLast 5LL

L2StreakL2

Injury report

Confirm lineups and injuries close to game time.

Houston Astros

Carlos Correa SS · Ankle - Surgery

Out

Brandon Walter SP · Elbow - Surgery

Out

Joey Loperfido LF · Hip - Surgery

Out

Chicago Cubs

Ben Brown RP · Neck - Fracture

Out

Riley Martin RP · Elbow - Strain

Out

Justin Steele SP · Elbow - Surgery

Out

Phil Maton RP · Knee - Sprain

Out

Shelby Miller RP · Elbow - Surgery

Out

Box score

Houston Astros

Player	H-AB	AB	R	H	RBI	HR	BB	K	#P	AVG	OBP	SLG
Jeremy Pena	1-5	5	0	1	0	0	0	1	19	.254	.297	.322
Isaac Paredes	1-4	4	1	1	0	0	1	0	20	.244	.335	.375
Yordan Alvarez	1-3	3	0	1	0	0	2	1	28	.303	.416	.601
Christian Walker	1-5	5	1	1	0	0	0	3	20	.254	.327	.481
Jake Meyers	1-4	4	0	1	0	0	0	1	9	.229	.296	.333
Braden Shewmake	0-1	1	1	0	0	0	1	0	7	.286	.298	.482
Brice Matthews	1-2	2	0	1	1	0	0	1	7	.207	.260	.355
Nick Allen	0-0	0	0	0	0	0	0	0	0	.235	.297	.265
Cam Smith	1-4	4	0	1	0	0	0	1	18	.207	.298	.317
Zach Cole	0-4	4	0	0	1	0	0	1	19	.170	.188	.383
Christian Vazquez	2-4	4	1	2	2	1	0	1	20	.258	.324	.430
Team	9-36	36	4	9	4	1	4	10	167

Houston Astros

Player	IP	H	R	ER	BB	K	HR	PC-ST	ERA	PC
Spencer Arrighetti	5.0	2	0	0	4	5	0	89-53	1.32	89
Steven Okert	0.1	2	2	2	0	0	1	6-5	4.22	6
Enyel De Los Santos	1.2	0	0	0	0	1	0	19-13	4.05	19
Bryan Abreu	0.2	0	0	0	1	0	0	14-6	7.31	14
Bryan King	1.1	0	0	0	0	0	0	17-12	2.82	17
Team	9.0	4	2	2	5	6	1	145-89		145

Chicago Cubs

Player	H-AB	AB	R	H	RBI	HR	BB	K	#P	AVG	OBP	SLG
Nico Hoerner	0-4	4	0	0	0	0	1	1	17	.259	.345	.383
Michael Busch	0-3	3	0	0	0	0	1	0	24	.229	.361	.369
Alex Bregman	1-3	3	0	1	0	0	1	0	19	.250	.338	.350
Ian Happ	1-5	5	0	1	0	0	0	2	18	.214	.350	.429
Seiya Suzuki	0-4	4	0	0	0	0	0	0	14	.254	.354	.435
Michael Conforto	0-2	2	0	0	0	0	0	1	8	.311	.419	.590
Miguel Amaya	1-1	1	1	1	0	0	0	0	2	.247	.360	.397
Moises Ballesteros	0-1	1	0	0	0	0	0	0	1	.241	.298	.446
Carson Kelly	0-3	3	0	0	0	0	0	1	15	.289	.377	.388
Pete Crow-Armstrong	1-2	2	1	1	2	1	2	0	16	.228	.311	.375
Dansby Swanson	0-4	4	0	0	0	0	0	1	11	.187	.289	.349
Team	4-32	32	2	4	2	1	5	6	145

Chicago Cubs

Player	IP	H	R	ER	BB	K	HR	PC-ST	ERA	PC
Jameson Taillon	4.2	8	4	4	1	5	1	90-59	5.20	90
Hoby Milner	0.1	1	0	0	0	0	0	8-5	1.93	8
Ethan Roberts	2.0	0	0	0	1	2	0	32-18	0.79	32
Jacob Webb	1.0	0	0	0	0	2	0	15-10	2.91	15
Phil Maton	1.0	0	0	0	2	1	0	22-11	8.40	22
Team	9.0	9	4	4	4	10	1	167-103		167

Recent form

Houston AstrosLL

Sep 30, 2026 · vs Chicago White SoxL 3-7

Sep 29, 2026 · vs Chicago White SoxL 3-6

Chicago CubsLL

Sep 30, 2026 · at San Diego PadresL 1-4

Sep 29, 2026 · at San Diego PadresL 0-8

Season series

HOU wins series 3-0

May 24, 2026HOU 8, CHC 5

May 23, 2026HOU 3, CHC 0

May 22, 2026HOU 4, CHC 2

Team pages

Houston Astros
Schedule, roster and stats

Chicago Cubs
Schedule, roster and stats

More MLB games on May 22, 2026

Cleveland Guardians1

Philadelphia Phillies0

Final

St. Louis Cardinals77-85

Washington Nationals4

Frequently asked questions

Who won Houston Astros vs Chicago Cubs?

Houston Astros won, 4-2, on Friday, May 22, 2026.

What was the final score of Houston Astros vs Chicago Cubs?

Houston Astros 4, Chicago Cubs 2.

Who were the top performers?

Houston Astros: Christian Vazquez (2-4, HR, 2 RBI, R, K batting average). Chicago Cubs: Pete Crow-Armstrong (1-2, HR, 2 RBI, R, 2 BB batting average).

Where is Houston Astros vs Chicago Cubs played?

Wrigley Field, Chicago, Illinois.

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Independent analysis for information and entertainment. Not betting advice. Scores, schedules, records and injuries can change.