Games / MLB / Sep 22, 2025

St. Louis Cardinals 6, San Francisco Giants 5: final score and stats

St. Louis Cardinals beat San Francisco Giants, St. Louis Cardinals 6 to San Francisco Giants 5, on Monday, September 22, 2025 at Oracle Park, San Francisco, California. Below: the box score, top performers, team stats, injuries and recent form for San Francisco Giants vs St. Louis Cardinals.

MLBMonday, September 22, 2025

St. Louis Cardinals77-806

Final

San Francisco Giants77-805

DateSep 22, 2025

Start time9:45 PM ET

VenueOracle Park, San Francisco, California

TVFanDuel SN MW, MLB.TV, NBC Sports BA

Attendance31,301

Line score

Team	1	2	3	4	5	6	7	8	9	R
St. Louis Cardinals	0	0	1	1	4	0	0	0	0	6
San Francisco Giants	1	0	0	3	1	0	0	0	0	5

Top performers

St. Louis Cardinals

Batting AverageAlec Burleson · 3-5, RBI, R, K

Home RunsIvan Herrera · 1-3, HR, 2 RBI, R, 2 BB

Runs Batted InIvan Herrera · 1-3, HR, 2 RBI, R, 2 BB

MLB RatingIvan Herrera · 1-3, HR, 2 RBI, R, 2 BB

San Francisco Giants

Batting AveragePatrick Bailey · 2-4, RBI, R

Home RunsRafael Devers · 1-3, HR, RBI, R, BB

Runs Batted InHeliot Ramos · 2-5, HR, 3 RBI, R, K

MLB RatingHeliot Ramos · 2-5, HR, 3 RBI, R, K

Team comparison

St. Louis CardinalsSan Francisco Giants

Runs per game

-

-

Runs allowed per game

-

-

77-80Record77-80

4th in NL CentStanding4th in NL West

0-0Road record / home record0-0

Last 5

-Streak-

Injury report

Confirm lineups and injuries close to game time.

St. Louis Cardinals

Richard Fitts SP · Lat - Surgery

Out

Max Rajcic RP · Elbow - Surgery

Out

Hunter Dobbins SP · Elbow - Surgery

Out

San Francisco Giants

Harrison Bader CF · Foot - Plantar Fasciitis

Out

Randy Rodriguez RP · Elbow - Surgery

Out

Rowan Wick RP · Elbow - Surgery

Out

Matt Chapman 3B · Abdomen - Surgery

Out

Rafael Devers 1B · Abdomen - Surgery

Out

Box score

St. Louis Cardinals

Player	H-AB	AB	R	H	RBI	HR	BB	K	#P	AVG	OBP	SLG
Lars Nootbaar	1-4	4	1	1	0	0	1	2	22	.236	.324	.365
Ivan Herrera	1-3	3	1	1	2	1	2	0	11	.281	.372	.462
Alec Burleson	3-5	5	1	3	1	0	0	1	18	.293	.345	.465
Nolan Arenado	1-5	5	1	1	0	0	0	3	22	.236	.290	.365
Thomas Saggese	1-5	5	0	1	0	0	0	1	12	.260	.304	.346
Pedro Pages	1-5	5	0	1	0	0	0	1	13	.232	.275	.368
Jordan Walker	0-3	3	1	0	1	0	1	0	18	.217	.279	.301
Jose Fermin	2-4	4	1	2	1	0	0	1	13	.315	.403	.463
Victor Scott II	0-2	2	0	0	0	0	0	0	8	.213	.301	.294
Team	10-36	36	6	10	5	1	4	9	137

St. Louis Cardinals

Player	IP	H	R	ER	BB	K	HR	PC-ST	ERA	PC
Michael McGreevy	5.0	6	5	5	3	2	2	90-49	4.35	90
Ryan Fernandez	1.1	1	0	0	0	1	0	11-9	7.62	11
John King	0.2	0	0	0	0	0	0	6-5	4.87	6
Kyle Leahy	1.0	0	0	0	1	1	0	21-10	3.21	21
JoJo Romero	1.0	0	0	0	0	1	0	19-13	2.09	19
Team	9.0	7	5	5	4	5	2	147-86		147

San Francisco Giants

Player	H-AB	AB	R	H	RBI	HR	BB	K	#P	AVG	OBP	SLG
Heliot Ramos	2-5	5	1	2	3	1	0	1	16	.258	.330	.396
Rafael Devers	1-3	3	1	1	1	1	1	0	14	.234	.344	.446
Willy Adames	0-4	4	0	0	0	0	0	0	15	.224	.318	.415
Matt Chapman	1-4	4	1	1	0	0	0	0	11	.232	.342	.432
Bryce Eldridge	0-2	2	0	0	0	0	2	0	21	.059	.273	.118
Christian Koss	0-0	0	0	0	0	0	0	0	0	.267	.305	.376
Casey Schmitt	1-4	4	1	1	0	0	0	1	12	.233	.304	.390
Patrick Bailey	2-4	4	1	2	1	0	0	0	19	.222	.278	.325
Jerar Encarnacion	0-4	4	0	0	0	0	0	2	16	.208	.222	.377
Drew Gilbert	0-2	2	0	0	0	0	1	0	14	.200	.247	.378
Wilmer Flores	0-1	1	0	0	0	0	0	1	9	.242	.308	.382
Team	7-33	33	5	7	5	2	4	5	147

San Francisco Giants

Player	IP	H	R	ER	BB	K	HR	PC-ST	ERA	PC
Justin Verlander	4.1	9	6	4	2	3	1	84-54	3.88	84
Tristan Beck	2.2	1	0	0	1	3	0	33-19	4.86	33
Matt Gage	1.0	0	0	0	1	1	0	9-5	2.93	9
Joel Peguero	1.0	0	0	0	0	2	0	11-8	2.79	11
Team	9.0	10	6	4	4	9	1	137-86		137

Season series

STL wins series 2-1

Sep 24, 2025STL 3, SF 4

Sep 23, 2025STL 9, SF 8

Sep 22, 2025STL 6, SF 5

Team pages

St. Louis Cardinals
Schedule, roster and stats

San Francisco Giants
Schedule, roster and stats

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Milwaukee Brewers4

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Frequently asked questions

Who won St. Louis Cardinals vs San Francisco Giants?

St. Louis Cardinals won, 6-5, on Monday, September 22, 2025.

What was the final score of St. Louis Cardinals vs San Francisco Giants?

St. Louis Cardinals 6, San Francisco Giants 5.

Who were the top performers?

St. Louis Cardinals: Alec Burleson (3-5, RBI, R, K batting average). San Francisco Giants: Patrick Bailey (2-4, RBI, R batting average).

Where is St. Louis Cardinals vs San Francisco Giants played?

Oracle Park, San Francisco, California.

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Independent analysis for information and entertainment. Not betting advice. Scores, schedules, records and injuries can change.