San Francisco 49ers 41, Arizona Cardinals 22: final score and stats
San Francisco 49ers beat Arizona Cardinals, San Francisco 49ers 41 to Arizona Cardinals 22, on Sunday, November 16, 2025 at State Farm Stadium, Glendale, AZ. Below: the box score, top performers, team stats, injuries and recent form for Arizona Cardinals vs San Francisco 49ers.
NFLSunday, November 16, 2025
DateNov 16, 2025
Start time4:05 PM ET
VenueState Farm Stadium, Glendale, AZ
TVFox
Attendance65,032
Line score
| Team | 1 | 2 | 3 | 4 | T |
|---|---|---|---|---|---|
| San Francisco 49ers | 13 | 12 | 10 | 6 | 41 |
| Arizona Cardinals | 7 | 3 | 0 | 12 | 22 |
Team comparison
San Francisco 49ersArizona Cardinals
Points per game
Points allowed per game
7-4Record3-7
1st in NFC WestStanding4th in NFC West
2-1Road record / home record0-3
WLWWWLast 5LWLWL
W1StreakL1
Team stats
San Francisco 49ersArizona Cardinals
1st Downs
Passing 1st downs
Rushing 1st downs
1st downs from penalties
3-93rd down efficiency6-14
0-04th down efficiency0-0
Total Plays
Total Yards
Yards per Play
Total Drives
Passing
19/26Comp/Att47/57
Yards per pass
Interceptions thrown
1-14Sacks-Yards Lost0-0
Rushing
Injury report
Confirm lineups and injuries close to game time.
San Francisco 49ers
C.J. West DT · Knee - Not Specified
Injured ReserveMike Evans WR · Achilles - Tendinitis
QuestionableDeommodore Lenoir CB · Foot - Not Specified
QuestionableRenardo Green CB · Back - Not Specified
QuestionableUpton Stout CB · Shoulder - Not Specified
QuestionableArizona Cardinals
Zachary Carter DT · Knee - Not Specified
Injured ReserveBam Knight RB · Concussion - Concussion
QuestionableAndrew Wingard S · Groin - Not Specified
QuestionableDante Stills DT · Shoulder - Not Specified
QuestionableMax Melton CB · Knee - Not Specified
QuestionableBox score
San Francisco 49ers Passing
| Player | C/ATT | YDS | AVG | TD | INT | SACKS | QBR | RTG |
|---|---|---|---|---|---|---|---|---|
| Brock Purdy | 19/26 | 200 | 7.7 | 3 | 0 | 1-14 | 71.2 | 133.5 |
| Team | 19/26 | 186 | 7.7 | 3 | 0 | 1-14 | -- | 133.5 |
San Francisco 49ers Rushing
| Player | CAR | YDS | AVG | TD | LONG |
|---|---|---|---|---|---|
| Christian McCaffrey | 13 | 81 | 6.2 | 2 | 20 |
| Brian Robinson Jr. | 8 | 24 | 3.0 | 0 | 7 |
| Mac Jones | 3 | -3 | -1.0 | 0 | -1 |
| Brock Purdy | 1 | -7 | -7.0 | 0 | -7 |
| Team | 25 | 95 | 3.8 | 2 | 20 |
San Francisco 49ers Receiving
| Player | REC | YDS | AVG | TD | LONG | TGTS |
|---|---|---|---|---|---|---|
| George Kittle | 6 | 67 | 11.2 | 2 | 30 | 6 |
| Jauan Jennings | 4 | 54 | 13.5 | 0 | 25 | 6 |
| Christian McCaffrey | 5 | 40 | 8.0 | 1 | 15 | 6 |
| Kyle Juszczyk | 2 | 26 | 13.0 | 0 | 21 | 2 |
| Demarcus Robinson | 1 | 13 | 13.0 | 0 | 13 | 2 |
| Brian Robinson Jr. | 0 | 0 | 0.0 | 0 | 0 | 1 |
| Ricky Pearsall | 1 | 0 | 0.0 | 0 | 0 | 2 |
| Team | 19 | 200 | 10.5 | 3 | 30 | 25 |
San Francisco 49ers Fumbles
| Player | FUM | LOST | REC |
|---|---|---|---|
| Keion White | 0 | 0 | 1 |
| Team | 0 | 0 | 1 |
San Francisco 49ers Defensive
| Player | TOT | SOLO | SACKS | TFL | PD | QB HTS | TD |
|---|---|---|---|---|---|---|---|
| Curtis Robinson | 12 | 5 | 0 | 0 | 0 | 0 | 0 |
| Dee Winters | 10 | 5 | 0 | 1 | 0 | 0 | 0 |
| Nick Martin | 7 | 5 | 0 | 0 | 0 | 0 | 0 |
| Deommodore Lenoir | 7 | 4 | 0 | 0 | 2 | 0 | 0 |
| Ji'Ayir Brown | 7 | 3 | 0 | 0 | 0 | 0 | 0 |
| Upton Stout | 7 | 2 | 0 | 0 | 0 | 0 | 0 |
| Renardo Green | 6 | 4 | 0 | 0 | 0 | 0 | 0 |
| Jason Pinnock | 5 | 3 | 0 | 1 | 0 | 0 | 0 |
| Team | 95 | 41 | 0 | 3 | 4 | 4 | 0 |
San Francisco 49ers Interceptions
| Player | INT | YDS | TD |
|---|---|---|---|
| Deommodore Lenoir | 1 | 64 | 0 |
| Malik Mustapha | 1 | 0 | 0 |
| Team | 2 | 64 | 0 |
San Francisco 49ers KickReturns
| Player | NO | YDS | AVG | LONG | TD |
|---|---|---|---|---|---|
| Skyy Moore | 1 | 98 | 98.0 | 98 | 0 |
| Brian Robinson Jr. | 1 | 42 | 42.0 | 42 | 0 |
| Team | 2 | 140 | 70.0 | 98 | 0 |
San Francisco 49ers PuntReturns
| Player | NO | YDS | AVG | LONG | TD |
|---|---|---|---|---|---|
| Skyy Moore | 1 | 9 | 9.0 | 9 | 0 |
| Team | 1 | 9 | 9.0 | 9 | 0 |
San Francisco 49ers Kicking
| Player | FG | PCT | LONG | XP | PTS |
|---|---|---|---|---|---|
| Eddy Pineiro | 3/3 | 100.0 | 48 | 2/4 | 11 |
| Team | 3/3 | 100.0 | 48 | 2/4 | 11 |
San Francisco 49ers Punting
| Player | NO | YDS | AVG | TB | In 20 | LONG |
|---|---|---|---|---|---|---|
| Thomas Morstead | 3 | 139 | 46.3 | 0 | 1 | 55 |
| Team | 3 | 139 | 46.3 | 0 | 1 | 55 |
Arizona Cardinals Passing
| Player | C/ATT | YDS | AVG | TD | INT | SACKS | QBR | RTG |
|---|---|---|---|---|---|---|---|---|
| Jacoby Brissett | 47/57 | 452 | 7.9 | 2 | 2 | 0-0 | 25.9 | 96.8 |
| Team | 47/57 | 452 | 7.9 | 2 | 2 | 0-0 | -- | 96.8 |
Arizona Cardinals Rushing
| Player | CAR | YDS | AVG | TD | LONG |
|---|---|---|---|---|---|
| Bam Knight | 5 | 24 | 4.8 | 1 | 7 |
| Emari Demercado | 5 | 8 | 1.6 | 0 | 5 |
| Michael Carter | 2 | 6 | 3.0 | 0 | 3 |
| Jacoby Brissett | 2 | -2 | -1.0 | 0 | 2 |
| Team | 14 | 36 | 2.6 | 1 | 7 |
Arizona Cardinals Receiving
| Player | REC | YDS | AVG | TD | LONG | TGTS |
|---|---|---|---|---|---|---|
| Michael Wilson | 15 | 185 | 12.3 | 0 | 34 | 18 |
| Trey McBride | 10 | 115 | 11.5 | 1 | 28 | 11 |
| Greg Dortch | 6 | 66 | 11.0 | 1 | 17 | 6 |
| Michael Carter | 5 | 22 | 4.4 | 0 | 7 | 7 |
| Bam Knight | 4 | 21 | 5.3 | 0 | 12 | 4 |
| Xavier Weaver | 2 | 15 | 7.5 | 0 | 9 | 3 |
| Emari Demercado | 2 | 12 | 6.0 | 0 | 9 | 3 |
| Elijah Higgins | 2 | 11 | 5.5 | 0 | 6 | 3 |
| Team | 47 | 452 | 9.6 | 2 | 34 | 56 |
Arizona Cardinals Fumbles
| Player | FUM | LOST | REC |
|---|---|---|---|
| Elijah Higgins | 1 | 1 | 0 |
| Team | 1 | 1 | 0 |
Arizona Cardinals Defensive
| Player | TOT | SOLO | SACKS | TFL | PD | QB HTS | TD |
|---|---|---|---|---|---|---|---|
| Cody Simon | 12 | 4 | 0 | 0 | 0 | 0 | 0 |
| Budda Baker | 8 | 3 | 0 | 0 | 0 | 0 | 0 |
| Jalen Thompson | 5 | 2 | 0 | 0 | 1 | 0 | 0 |
| Darius Robinson | 5 | 1 | 0 | 0 | 0 | 0 | 0 |
| Max Melton | 4 | 2 | 0 | 0 | 1 | 0 | 0 |
| Akeem Davis-Gaither | 4 | 1 | 0 | 0 | 0 | 0 | 0 |
| PJ Mustipher | 3 | 2 | 0 | 0 | 0 | 0 | 0 |
| Garrett Williams | 3 | 1 | 0 | 0 | 1 | 0 | 0 |
| Team | 59 | 28 | 1 | 3 | 4 | 3 | 0 |
Arizona Cardinals KickReturns
| Player | NO | YDS | AVG | LONG | TD |
|---|---|---|---|---|---|
| Greg Dortch | 3 | 79 | 26.3 | 31 | 0 |
| Andre Baccellia | 3 | 74 | 24.7 | 27 | 0 |
| Michael Carter | 1 | 27 | 27.0 | 27 | 0 |
| Team | 7 | 180 | 25.7 | 31 | 0 |
Arizona Cardinals PuntReturns
| Player | NO | YDS | AVG | LONG | TD |
|---|---|---|---|---|---|
| Greg Dortch | 2 | 51 | 25.5 | 40 | 0 |
| Team | 2 | 51 | 25.5 | 40 | 0 |
Arizona Cardinals Kicking
| Player | FG | PCT | LONG | XP | PTS |
|---|---|---|---|---|---|
| Chad Ryland | 1/2 | 50.0 | 26 | 1/1 | 4 |
| Team | 1/2 | 50.0 | 26 | 1/1 | 4 |
Arizona Cardinals Punting
| Player | NO | YDS | AVG | TB | In 20 | LONG |
|---|---|---|---|---|---|---|
| Pat O'Donnell | 3 | 122 | 40.7 | 0 | 0 | 46 |
| Team | 3 | 122 | 40.7 | 0 | 0 | 46 |
Recent form
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Frequently asked questions
Who won San Francisco 49ers vs Arizona Cardinals?
San Francisco 49ers won, 41-22, on Sunday, November 16, 2025.
What was the final score of San Francisco 49ers vs Arizona Cardinals?
San Francisco 49ers 41, Arizona Cardinals 22.
Where is San Francisco 49ers vs Arizona Cardinals played?
State Farm Stadium, Glendale, AZ.
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